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Dipeptidyl peptidase-IV
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Dipeptidyl peptidase-IV

Acid stable Dipeptidyl Peptidase- IV(DPP IV) is prolyl endopeptidase (EC 3. 4. 21. 26), also called prolinespecific endoprotease, originated from Aspergillusoryzae,belongs to the serine protease family and has the ability to cleave peptides at internal proline residues.

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Product Description


Acid stable Dipeptidyl Peptidase-IV(DPP IV)


Description:

Acid stable Dipeptidyl Peptidase-IV (DPP IV) is prolyl endopeptidase (EC 3. 4. 21. 26), also called prolinespecific endoprotease, originated from Aspergillusoryzae,belongs to the serine protease family and has the ability to cleave peptides at internal proline residues.


Characteristics:
 Acid stable Dipeptidyl Peptidase-IV (DPP IV) can efficiently cleave the peptide bond involving proline residues of proline-rich proteinswhich isthe most frequent cause of haze in beer, wine,and clear fruit juices due to protein–polyphenol interaction, such as casein, gluten, collagen, and gelatin.

Product source:

The Protease Dipeptidyl Peptidase-IV produced by our company comes from Aspergillus oryzaeand it is a kind of food grade enzyme preparation which is formed by the method of biological fermentation.


Product application
One in three consumers (31 percent of the UK and 36 percent of the US) are inclined to limit their intake or avoid gluten. Gluten in wheat, barley and rye consists of several different proteins – the two main groups are gliadin and glutenin. Gluten proteins that is rich in proline, an amino acid, are extremely difficult to digest. Undigested gluten proteins trigger the immune system to attack the inner lining of the small intestine, resulting in varying levels of gluten sensitivity. Breaking down these proteins can help alleviate the symptoms associated with gluten sensitivity and prevent further damage to the body.
Acid stable Dipeptidyl Peptidase-IV (DPP IV):
is a micro-granulate with excellent flowability and compressibility for use in tablets and capsules.
has an high solubility and a bland taste.
has good stability at temperatures ≤ 40°C and a shelf life of 24 months at ≤ 15 °C.

The dose rate is dependent on the sensitivity of gluten intolerance and the size of meal consumed. Newgen experts remain at your disposal to advise on the most appropriate dose and the consumer intake.


Packaging And Storage:
Solid for food packaging bags,25 kg/bucket. (it can be packaged according to customer requirements).

Dipeptidyl Peptidase-IV is very sensitive to temperature, light, humidity, do as much as possible during transport and storage to avoid exposure, high temperature, humidity and keep clean, cool and dry. It can be better if stored in low temperature.


The enzymatic properties of Acid Stable Dipeptidyl Peptidase-IV (DPP IV)

1.Heat resistance2.PH tolerance

3.Optimum reaction temperat4. Optimal reaction pH

5. Comparative analysis

CERTIFICATE OF ANALYSIS


Product Name Dipeptidyl Peptidase-IV    
Other Name NA Country of Origin China
Strain Aspergillus niger Manufacture Date NOV 17, 2018
Batch Number DPP18111901 Expiration Date NOV 16, 2020
Package 25 kg/bucket Quantity 125 kg
PROTOCOL SPECIFICATIONS RESULTS METHOD
PHYSICAL & CHEMICAL ANALYSIS
Description Light yellow or light brown powder Complies Visual
Odor & Taste Characteristic odor and taste Complies Taste
Moisture NMT 7% 3.9% Moisture Analyzer
IDENTIFICATION
Identifiable Activity Positive for Serratiopeptidase Activity Complies In-house
ACTIVITY
DPPⅣ activity NLT10,000 U/g 10,100 U/g In-house
MICROBIOLOGICAL
Total bacteria count
Coliform bacteria (CFU/g)
Molds and Yeasts
E.Coli
Salmonella
Staphylococcus aureus
Pseudomonas aeruginosa
NMT 3,000 CFU/g
NMT 30 CFU/g
NMT 100 CFU/g
Absent
Absent
Absent
Absent
Complies
Complies
Complies
Complies
Complies
Complies
Complies
FDA BAM Online Ch.3
FDA BAM Online Ch.4
FDA BAM Online Ch. 2
FDA BAM Online Ch.4
FDA BAM Online Ch.5
FDA BAM Online Ch.12
AOAC
HEAVY METALS
Lead
Mercury
Cadmium
Arsenic
NMT 3 ppm
NMT 0.1 ppm
NMT 1 ppm
NMT 1 ppm
Complies
Complies
Complies
Complies
USP <231>
USP <231>
USP <231>
USP <231>
Storage: Store in cool and dry place protected from light, keep drum close when not in use.
Conclusion:Conforms to FCC Standards.
Shelf Life: Shelf life under prescribed storage conditions and air-tight packing will be 2 years.
The product COMPLIES with the above said specifications
Approved by RICKY H. ZHU Authorized Signatory


Packaging and storage

Solid food packaging bag, 25 kg / barrel.


Dipeptidyl Peptidase-IV should be stored in dry, cool and well ventilated places away from the sun, heat.

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